Expertises & services
Our laboratory has been collaborating with numerous national and international Universities and private research facilities. If you are interested in collaboration, please feel free to contact us.
Bio-artificial muscle
Human skeletal muscle tissues based on myoblasts and fibroblasts are embedded in fibrin or collagen hydrogels. The myogenic cells fuse and form aligned 3D myofiber bundles, capable of force generation. Our lab has expertise in 3D tissue engineering methods, and analysis of 3D cell-cell and cell-materials interaction.
Cell Culture
Our laboratory has a wide expertise regarding cell culture, going from cell storage and expansion to multiple assays.
Histology
Parafin – and cryosectioning. Several staining methods are routinely used including H&E, Masson’s trichrome, Martius Scarlet Blue, Alcian Blue as well as a whole array of immunofluorescence markers.
Microscopy
An extensive use of multiple microscopic techniques such as confocal, fluorescence and lighsheet microscopy for various tissue types.
Generation of spheroids
High-throughput generation of cellular spheroids (diameter between 100-300 µm) and their phenotypic differentiation to mimick several tissue types (fibrocartilage, cartilage, bone, adipose tissue, myogenic tissue, vascularized tissue,… ) starting from primary adult cells or mesenchymal stem cells.
Bioprinting
We study the impact and characteristics of different hydrogels (cell interactivity, mechanical strength, porosity,…) and crosslinking methods on the phenotype of multiple cells and cellular spheroids after encapsulation or bioprinting.
Decellularization
We remove cells from tissue or an organ to isolate the extracellular matrix. The aim is to use this structure with a preserved architecture to support cell growth and facilitate tissue regeneration.
Our research is mainly performed at the interdisciplinary research facilities (IRF), where we use common infrastructure with other research groups. More information about these facilities and research topics can be found on their website.